ncRNA name | hsa-miR-17-3p |
ncRNA Category | miRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | Macular RPE cells, human retinal pigment epithelium and ARPE-19 |
Methods | transfection, RT-PCR, Western blot, TUNEL assay |
Expression pattern | up-regulated |
Functional description | miR-17-3p aggravates oxidative damage-induced cell death in human RPE cells, while miR-17-3p inhibitor acts as a potential protector against oxidative stress by regulating the expression of antioxidant enzymes. |
PubMed ID | 27505139 |
Year | 2016 |
Title | miR-17-3p Exacerbates Oxidative Damage in Human Retinal Pigment Epithelial Cells. |
Drug-related ncRNA | NO |
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