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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name hsa-miR-17-3p
ncRNA Category miRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line Macular RPE cells, human retinal pigment epithelium and ARPE-19
Methods transfection, RT-PCR, Western blot, TUNEL assay
Expression pattern up-regulated
Functional description miR-17-3p aggravates oxidative damage-induced cell death in human RPE cells, while miR-17-3p inhibitor acts as a potential protector against oxidative stress by regulating the expression of antioxidant enzymes.
PubMed ID 27505139
Year 2016
Title miR-17-3p Exacerbates Oxidative Damage in Human Retinal Pigment Epithelial Cells.
Drug-related ncRNA NO

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